What is the target ETCO2 range after ROSC?

• A. 25-35 mmHg
• B. 35-45 mmHg
• C. 45-55 mmHg
• D. 50-60 mmHg

Answer: (B)

End-tidal CO2 after ROSC is used as a quick, noninvasive gauge of how well ventilation and perfusion are working together. Once circulation is restored, keeping ETCO2 in the normal range helps ensure CO2 is being eliminated properly and cerebral perfusion remains stable. The appropriate target is about 35-45 mmHg because this mirrors normal arterial CO2 and reflects balanced ventilation and perfusion. If ETCO2 is too low, it can indicate poor perfusion or overly aggressive ventilation, while ETCO2 above this range points to hypoventilation and rising CO2, which can worsen acidosis and raise intracranial pressure. So aim for roughly 35-45 mmHg to optimize post-ROSC stability.