Which receptor is primarily responsible for bronchodilation?

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Multiple Choice

Which receptor is primarily responsible for bronchodilation?

Explanation:
Bronchodilation is driven by beta-2 adrenergic receptors on bronchial smooth muscle. When these receptors are activated by sympathetic agonists, they stimulate a Gs protein to raise cyclic AMP, which relaxes the smooth muscle and widens the airways. This is the primary mechanism behind inhaled beta-2 agonists like albuterol that relieve bronchospasm. Beta-1 receptors are mainly in the heart and affect heart rate and contractility, not airway tone. Alpha-1 receptors cause vasoconstriction in vascular smooth muscle, not bronchodilation. Dopaminergic receptors have other roles in the body and do not primarily control airway dilation.

Bronchodilation is driven by beta-2 adrenergic receptors on bronchial smooth muscle. When these receptors are activated by sympathetic agonists, they stimulate a Gs protein to raise cyclic AMP, which relaxes the smooth muscle and widens the airways. This is the primary mechanism behind inhaled beta-2 agonists like albuterol that relieve bronchospasm. Beta-1 receptors are mainly in the heart and affect heart rate and contractility, not airway tone. Alpha-1 receptors cause vasoconstriction in vascular smooth muscle, not bronchodilation. Dopaminergic receptors have other roles in the body and do not primarily control airway dilation.

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