Which statement about Vecuronium is true?

• A. Depolarizing neuromuscular blocker.
• B. Inhaled anesthetic.
• C. Non-depolarizing neuromuscular blocker; Excreted through kidneys.
• D. Opioid analgesic.

Answer: (C)

Vecuronium is a nondepolarizing neuromuscular blocker used to produce skeletal muscle relaxation during anesthesia. It works by competitively blocking acetylcholine at nicotinic receptors on the neuromuscular junction, preventing depolarization and causing flaccid paralysis without the fasciculations seen with depolarizing agents. It is not a depolarizing agent, not an inhaled anesthetic, and not an opioid analgesic. In terms of elimination, it is primarily metabolized by the liver with biliary excretion, and its metabolites are cleared by the kidneys, so renal excretion contributes to its elimination. This is why kidney function can influence how long its effects last and why dosing may need adjustment in renal impairment. Reversal of its effects can be achieved with acetylcholinesterase inhibitors or sugammadex where available.